First deCODE publication based on Illumina genome-wide association scan, identifying a second major prostate cancer risk variant on chromosome 8q24.
This is the first deCODE publication emerging from the application of Illumina’s genome-wide SNP association technologies. In the study, a team of deCODE scientists and academic colleagues from the United States, Iceland, Spain and the Netherlands, identified a second genetic variant on chromosome 8q24, conferring risk of prostate cancer.
The variant was identified through a genome-wide association scan of 4,500 Icelandic cases and controls using the Illumina HumanHap300 Bead Chip, which types more than 300,000 SNPs across the genome.
The article, entitled “Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24”, is published in the online edition of Nature Genetics, at www.nature.com/ng, and will be published in a subsequent print edition of the journal.
The publication has already been widely covered by the media, e.g. by The Independent, Newsweek, and Bloomberg.