NEWS

A sequence variant that increases risk of pregnancy loss

A sequence variant that increases risk of pregnancy loss

Scientists at deCODE genetics, a subsidiary of Amgen, and their collaborators from Iceland, Denmark, and the USA published a study today in Nature Structural and Molecular Biology titled “Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effects on recombination”.

read more
Epidemiology and Genetics of Clonal Hematopoiesis, a Premalignant Hematopoietic Stem Cell Condition

Epidemiology and Genetics of Clonal Hematopoiesis, a Premalignant Hematopoietic Stem Cell Condition

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis. Whole genome sequence data from Iceland and the UK Biobank, combined with a unique somatic mutation Barcoding strategy, was used to investigate clonal hematopoiesis at the population scale.

read more
Large-scale proteomics in population-based studies from UK and Iceland

Large-scale proteomics in population-based studies from UK and Iceland

In a paper released today, deCODE Genetics’ scientists shared their findings from a plasma proteomics study performed using affinity-based methods. They analyzed the proteins in the context of diseases and diversity in the sequence of the genome and compared measurements made using two platforms of thousands of proteins in samples from large groups from the UK Biobank and Iceland.

read more
Variants in the genome interact with each other and with the environment to affect risk of cardiovascular disease

Variants in the genome interact with each other and with the environment to affect risk of cardiovascular disease

Scientists at deCODE genetics, a subsidiary of Amgen, and their collaborators from the Icelandic healthcare system and  Copenhagen University, published a study today in the journal Cell titled “Complex effects of sequence variants on lipid levels and coronary artery disease”. The work described in the paper is based on searching for variants in the genome that are associated with variance in quantitative traits and the assumption that those variants must interact either with other variants or components of the environment.

read more
CRTAC1 is a promising biomarker of osteoarthritis

CRTAC1 is a promising biomarker of osteoarthritis

CRTAC1 in plasma is a specific biomarker of osteoarthritis, a measure of OA risk, and a predictor of progression to joint replacements. The lack of a biomarker of osteoarthritis (OA) has hindered the development of effective therapies for this common disease.

read more
Rounding off the human genome

Rounding off the human genome

In a study published today, scientists at deCODE Genetics demonstrate for the first time how long-read DNA sequencing can be applied at population scale to unravel large structural variants that associate with human disease and other traits.

read more
Monozygous but not identical

Monozygous but not identical

By sequencing the germline genomes of twins and comparing them to those of close relatives, scientists at deCODE genetics found mutations that are present in just one of the monozygotic twins and traced them back to the first days after conception.

read more
Iceland Provides a Picture of the Early Spread of COVID-19 in a Population With a Cohesive Public Health Response

Iceland Provides a Picture of the Early Spread of COVID-19 in a Population With a Cohesive Public Health Response

Study combines the most intensive targeted testing and general screening of any population to date with comprehensive sequencing of the virus from all identified cases, to trace its mutation and spread
Results underscore the effectiveness and necessity of aggressive testing, isolation of cases and physical distancing, as well as the urgency of more testing to contain the virus and disease

read more
Kári Stefánsson elected to  National Academy of Science

Kári Stefánsson elected to National Academy of Science

Kári Stefánsson, the founder and CEO of deCODE Genetics, now a subsidiary of Amgen, has been elected to the National Academy of Science (NAS). Election to the academy is one of the highest honors in the field of science and a recognition reserved for individuals whose careers are distinguished by original and continuing achievements in their areas of research.

read more

The Genomic Portrait of a Nation

The largest studies of whole-genome data ever published reveal the power of the sequencing revolution for understanding the roots of disease, diversity and evolution: The most comprehensive population-wide tally to date of sequence variation A nationwide collection of...

read more

The New deCODE Map of the Human Genome

The most detailed template yet of the different ways in which women and men, individuals and populations, are driving one of the main motors of evolution. Reykjavik, ICELAND, 27 October 2010 – Scientists from deCODE genetics today publish in Nature the highest...

read more

Announcing the New deCODE

Reykjavik, ICELAND, January 21, 2010 – deCODE genetics ehf today emerged as a newly financed, private company focused on advancing the science of human genetics and its application to products and services that improve human health. The new company will be building on...

read more

deCODE Launches deCODEme™

The company that has led in the discovery of genes that confer risk of common diseases is empowering individuals to explore their own genome Reykjavik, ICELAND, Nov. 16, 2007 – deCODE genetics (Nasdaq:DCGN) today announced the launch of deCODEme™, a pioneering service...

read more

deCODE Discovers a Variation in the Sequence of the Genome Conferring Risk of Atrial Fibrillation Launches deCODE AF™, A Test for the Risk Variant Aimed at the Prevention of Stroke

A paper published today in the journal Nature describes the discovery by scientists at deCODE genetics (Nasdaq:DCGN), in collaboration with academic colleagues in Iceland, the United States, Sweden and China, of two common single-letter variations in the genome (SNPs)...

read more

deCODE and Roche Diagnostics Announce Discovery of Significant Genetic Risk Factors for Heart Attack DNA-based diagnostics applying these findings may enable more targeted, individualized prevention strategies

Reykjavik, ICELAND, and Basel, SWITZERLAND, October 17, 2003 — deCODE genetics (Nasdaq/Nasdaq Europe:DCGN) and Roche Diagnostics today announced a landmark discovery under their alliance to develop DNA-based diagnostic tests for common diseases. deCODE scientists have...

read more

Roche Announces Mapping of Stroke Gene

March 29, 2000 Roche announced today that scientists at deCODE genetics, based in Reykjavik, Iceland, have reached an important milestone in their collaborative research on the genetics of common forms of stroke by successfully mapping a gene that contributes to the...

read more