Multiomics study of nonalcoholic fatty liver disease

Scientists at deCODE genetics in Iceland have discovered rare, protective loss-of-function variants that point to potential drug targets for nonalcoholic fatty liver disease (NAFLD). Kari Stefansson CEO of deCODE genetics and senior author on the paper and Gardar...

CRTAC1 is a promising biomarker of osteoarthritis

CRTAC1 in plasma is a specific biomarker of osteoarthritis, a measure of OA risk, and a predictor of progression to joint replacements. The lack of a biomarker of osteoarthritis (OA) has hindered the development of effective therapies for this common disease. Kari...

25th anniversary of deCODE genetics

DeCODE genetics celebrated its 25th anniversary with a two-day conference in Reykjavik on the 18 and 18th of May. The first day was dedicated to deCODES contributions to the Study of Human Diversity over 25 years. The second day was committed to Human Diversity,...

Rounding off the human genome

 In a study published today, scientists at deCODE Genetics demonstrate for the first time how long-read DNA sequencing can be applied at population scale to unravel large structural variants that associate with human disease and other traits. In a paper...

Monozygous but not identical

By sequencing the germline genomes of twins and comparing them to those of close relatives, scientists at deCODE genetics found mutations that are present in just one of the monozygotic twins and traced them back to the first days after conception. In the article,...